Detrimental role of humoral signalling in cardio-renal cross-talk

نویسندگان

  • Vincenzo Cantaluppi
  • Sergio Dellepiane
  • Alessandro D Quercia
  • Silvia Ferrario
چکیده

In critically ill patients, any acute organ injury is associated with a sudden change of circulating factors that may play a role in distant organ dysfunction through a complex cross-talk. In this issue, Virzì and colleagues discuss the relevance of humoral signalling between heart and kidney, focusing on type 1 and type 3 cardio-renal syndrome. We herein review the mechanisms of heart-kidney cross-talk, discussing the role of circulating detrimental mediators in the pathogenetic mechanisms of cardio-renal syndrome.

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عنوان ژورنال:

دوره 18  شماره 

صفحات  -

تاریخ انتشار 2014